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      1. CATALYTIC CO2 REDUCTION BY PALLADIUM
        DECORATED SILICON HYDRIDE NANOSHEETS
        The Ozin Group shows how decorating silicon nonosheets with palladium
        nanoparticles renders the process catalytic, a breakthrough with far
        reaching technological implications.
        Ozin group, Nature Catalysis, 2019
      2. UNUSUAL REARRANGEMENT OF AN
        N-DONOR-FUNCTIONALIZED N-HETEROCYCLIC
        CARBENE LIGAND ON GROUP 8 METALS
        The Song group discovered an unusual rearrangement reaction,where
        the N,C-chelate ligand of a piano-stool Group 8complex isomerizes into
        an N,N-chelate ligand. Mechanistic study suggests the involvement of a
        high-energy metal-alkylidene intermediate.
        Song group, Journal of the American Chemical Society, 2018
      3. DYSREGULATION OF MITOCHONDRIAL CLPP
        PROTEASE AS A POTENTIAL STRATEGY TO
        DEVELOP NOVEL ANTICANCERS
        Human mitochondrial ClpP was found to be activated by specific
        acyldepsipeptide compounds causing apoptotic cell death.
        Houry and Batey groups, Cell Chemical Biology, 2018
      4. AMINE HEMILABILITY ENABLES BORON TO
        MECHANISTICALLY RESEMBLE EITHER
        HYDRIDE OR PROTON
        Mechanistic studies of the hemilability of MIDA
        (N-methyliminodiacetic acid) boronates reveal the chameleonic
        behaviour of the BMIDA group.
        Yudin group, Nature Chemistry, 2018
      5. TIPPING CELL SIGNALING PATHWAYS BY SALTS
        Mechanistic insights into allosteric regulation ofthe A2A adenosine
        G protein-coupled receptor byphysiological cations.
        Prosser group, Nature Communications, 2018
      6. COMPETITIVE SELF-ASSEMBLY KINETICS AS A
        ROUTE TO CONTROLLING MORPHOLOGY OF
        CORE-CRYSTALLINE CYLINDRICAL MICELLESS
        One can manipulate the seeded-growth kinetics of block
        copolymer unimers to control the growth sequence of
        unimers and thus the comicelle morphology.
        Winnik group, Journal of the American Chemical Society, 2018
      7. INHIBITING MYC BINDING TO THE E-BOX DNA
        MOTIF BY ME47 DECREASES
        TUMOUR XENOGRAFT GROWTH
        The Shin lab's designed protein ME47 decreased tumor growth in
        a triple negative breast cancer mouse model, a type of cancer with
        no effective treatments.
        Shin, Chan & Penn groups, Oncogene, 2017

      Awards:

      Austin Marchese named 2019 Vanier Scholar

      This week, Austin Marchese was named one of 2019抯 Vanier Scholars, Canada抯 most prestigious award for doctoral studies.

      Austin, who is supervised by Professor Mark Lautens, is recognized for his research proposal "Novel Enantioselective Nickel-Catalyzed Transformations Forming Medicinally and Industrially Relevant Halogenated Compounds".


      News and Announcements:

      Nimrat Obhi earns place in 'Periodic Table of Younger Chemists'

      Announced this week at the 102nd Canadian Chemistry Conference and Exhibition in Qu閎ec City, Nimrat Obhi (Seferos Group) received a special recognition from the International Union of Pure and Applied Chemistry (IUPAC).

      Nimrat was placed in IUPAC's Periodic Table of Younger Chemists, which recognizes 118 outstanding "younger chemists from around the world leading us into the next century".


      Global Carbon Dioxide Cooling

      It may come as a surprise, but carbon dioxide, the infamous greenhouse gas driving climate change, is also a leading contender in the replacement of hydrofluorocarbons in the next-generation of 揼reen?refrigeration systems.

      It offers many advantages over second and third generation refrigerants, including higher volumetric cooling capacity, lower operating temperatures, non-flammability, reduced operating costs, and lower global warming potential. Read more from Professor Geoffrey Ozin in Advanced Science News


      Professor Eugenia Kumacheva wins de Gennes Prize

      Professor Eugenia Kumacheva has been named winner of the prestigious de Gennes Prize awarded biannually for outstanding and exceptional work in the field of materials chemistry by the Royal Society of Chemistry (U.K.)

      Prof. Kumacheva has won the award for the design of soft and self-assembled new materials with biomedical applications.


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      On the occasion of its 5th anniversary, Advanced Science抯 virtual issue collects a celebratory series of invited-only articles which showcase the outstanding achievements of leading international r...

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